首页|亚麻醉剂量艾司氯胺酮在瘢痕子宫产妇再次剖宫产术的应用

亚麻醉剂量艾司氯胺酮在瘢痕子宫产妇再次剖宫产术的应用

Application of subanesthetic dose of esketamine in pregnant women with scar uterus undergoing second Cesarean section

扫码查看
目的 观察亚麻醉剂量艾司氯胺酮在瘢痕子宫产妇再次剖宫产术的应用效果.方法 160例瘢痕子宫产妇随机分为艾司氯胺酮(E)组和生理盐水(C)组,每组80例.两组产妇在腰-硬联合麻醉下行剖宫产术;待胎儿娩出断脐后,E组静脉给予亚麻醉剂量艾司氯胺酮0.3mg/kg,C组静脉给予等体积的生理盐水.记录两组产妇术中牵拉反应和术后不良反应发生情况,评估Ramsay镇静评分、简易智力状态检查量表(MMSE)评分和产妇满意度评分.结果 与C组比较,E组牵拉反应0级发生率较高,1级和2级发生率较低(P<0.05).给药后30 min和1 h,E组Ramsay镇静评分高于C组,寒战、恶心、呕吐发生率低于C组(P<0.05).E组产妇满意度评分高于C组(P<0.05).两组产妇MMSE评分比较差异无统计学意义(P>0.05).结论 瘢痕子宫产妇再次剖宫产术中应用亚麻醉剂量艾司氯胺酮,能有效减轻牵拉反应,镇静效果较好,术后不良反应少,产妇满意度高.
Objective To observe the application efficiency of subanesthetic dose of esketamine in pregnant women with scar uterus undergoing second Cesarean section.Methods A total of 160 pregnant women with scar uterus were divided into groups of E and C with 80 cases each.The patients in two groups were delivered by Cesarean section under combined spinal-epidural anesthesia.After fetus delivered and the umbilical cord was ligated,group E was given subanesthetic dose of esketamine 0.3 mg/kg intravenously,and group C was given equal volume of normal saline.The occurrences of traction reaction and postoperative adverse reaction were recorded.Ramsay sedation score,mini-mental state examination(MMSE)score and maternal satisfaction score were evaluated.Results Compared with group C,the incidence of traction reaction grade 0 was higher,the incidences of grade 1 and grade 2 were lower,Ramsay sedation scores at 30 minutes and one hour after administration were higher,the incidences of chill,nausea and vomiting were lower,and maternal satisfaction score was increased in group E(P<0.05).There was no significant difference in MMSE score between the two groups(P>0.05).Conclusion The application of subanesthetic dose of esketamine in pregnant women with scar uterus undergoing second Cesarean section can effectively reduce traction reaction and has better sedation effect,less postoperative adverse reaction and better maternal satisfaction.

EsketamineSubanesthetic doseScar uterusCesarean section

王朝辉、张盼盼、李彩娟、袁红梅、冯善武

展开 >

210004 江苏,南京医科大学附属妇产医院(南京市妇幼保健院)麻醉科

艾司氯胺酮 亚麻醉剂量 瘢痕子宫 剖宫产

南京医科大学发展基金面上项目

2017NJMU078

2024

江苏医药
江苏省人民医院(南京医科大学第一附属医院)

江苏医药

影响因子:0.707
ISSN:0253-3685
年,卷(期):2024.50(3)
  • 18