Objective To explore the value of D-dimer and platelet count in predicting Henoch-Schönlein purpura nephritis(HSPN).Methods A total of 68 children diagnosed with Henoch-Schönlein purpura(HSP)were divided into two groups of A(without nephritis,38 cases)and B(with HSPN,30 cases).The value of D-dimer and platelet count in predicting HSPN was analyzed.Results The levels of D-dimer and platelet count in group B were significantly higher than those in group A(P＜0.05).Univariate logistic regression analysis showed that higher D-dimer and platelet count were the risk factors for HSPN(P＜0.05).The AUC values for D-dimer and platelet count were 0.903 and 0.846,respectively and the sensitivity and specificity in predicting HSPN were over 80％.Conclusion The children with HSPN have higher D-dimer and platelet count.The increase of both D-dimer and platelet count are the risk factors for HSPN,suggesting that HSP children with increased D-dimer and platelet count should be treated promptly and observed closely to minimize the occurrence of HSPN.
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