Objective To explore the predictive value of three-dimensional speckle tracking imaging(3D-STD for left ventricular remodeling after percutaneous coronary intervention(PCI)in the patients with acute myocardial infarction(AMI).Methods A total of 178 patients with AMI underwent PCI were divided into two groups of A(left ventricular remodeling,45 cases)and B(non-left ventricular remodeling,133 cases)according to one-year follow-up.The clinical data and left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume(LVEDV)and left ventricular global longitudinal strain(LVGLS)at immediately,72 hours,one week,one month and one year after PCI were compared between the two groups.ROC curves were drawn to analyze the predictive value of LVGLS at different time points for left ventricular remodeling after PCI in AMI patients,and the influencing factors for left ventricular remodeling after PCI in AMI patients were analyzed by multivariate logistic regression.Results There were significant differences in the proportions of the patients with diabetes history,infarct site,and the number of coronary artery lesions,and serum levels of uric acid(UA)and cystatin C(CysC)between the two groups(P<0.01).Compared with group B,LVEF was decreased and LVEDV was increased at one month and one year after PCI,LVGLS was increased at 72 hours,one week,one month and one year after PCI in group A(P<0.01).LVGLS at 72 hours,one week,one month and one year after PCI had predictive value for left ventricular remodeling in AMI patients(P<0.01).The anterior wall,the increase of serum levels of UA and CysC,the increase of LVEDV and LVGLS at one month after PCI were the risk factors(P<0.05),and the increase of LVEF one month after PCI was a protective factor for left ventricular remodeling in AMI patients(P<0.05).Conclusion 3D-STI has a good predictive value for left ventricular remodeling after PCI in patients with AMI.