Value of multi-row spiral computed tomography in differentiating benign and malignant solitary pulmonary nodules
Objective To investigate the value of multi-row spiral computed tomography(MSCT)in differentiating benign and malignant solitary pulmonary nodules(SPNs).Methods The clinical data and MSCT imaging characteristics of 73 patients with SPNs were retrospectively analyzed.According to pathological diagnosis,the patients were divided into two groups of M(with malignant SPNs,49 cases)and B(with benign SPNs,24 cases).The differences of clinical data and MSCT imaging characteristics were compared between the two groups.Results Compared with group B,group M had higher proportion of diameter＞10 mm(89.8％vs.70.8％),irregular shape(75.5％vs.33.3％),clear but uneven nodule-lung interface(83.7％vs.20.8％),lobulation(83.7％vs.41.7％),spiculation(73.5％vs.16.7％),pleural indentation sign(57.1％vs.20.8％),vascular convergence sign(55.1％vs.25.0％),vacuole or bronchial air sign(63.3％vs.45.8％),and subsolid nodules(63.3％vs.25.0％),and lower proportion of calcification(2.0％vs.16.7％)(P＜0.05).Conclusion Many MSCT features of the malignant SPNs are obviously different from those of the benign SPNs.Combined with the comprehensive analysis of clinical data is beneficial for improving the value of MSCT in distinguishing benign and malignant SPNs.
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