首页|三酰甘油葡萄糖指数对老年2型糖尿病患者发生冠心病的诊断价值

三酰甘油葡萄糖指数对老年2型糖尿病患者发生冠心病的诊断价值

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目的 探讨三酰甘油葡萄糖(TyG)指数对老年2型糖尿病(T2DM)患者发生冠心病的诊断价值.方法228例老年T2DM患者依据冠状动脉造影结果分为试验组(发生冠心病,149例)和对照组(未发生冠心病,79例).比较两组相关临床资料,采用多因素logistic回归分析老年T2DM患者发生冠心病的危险因素,ROC曲线评估TyG指数对老年T2DM患者发生冠心病的诊断价值.结果 试验组患者高血压比例、HbA1c、FBG、TG、TC、LDL-C、AST、Plt、TyG指数高于对照组(P<0.05).高血压以及高AST、高TyG指数为老年T2DM患者发生冠心病的独立危险因素(P<0.05).TyG指数诊断老年T2DM患者发生冠心病的曲线下面积为0.808[95%CI(0.748~0.867)](P<0.01),当TyG指数取最佳诊断界值为9.028时,诊断的灵敏度为64.6%,特异度为81.9%.结论TyG指数对老年T2DM患者发生冠心病具有较好的诊断价值.
Diagnostic value of triglyceride glucose index for coronary heart disease in elderly patients with type 2 diabetes mellitus
Objective To investigate the diagnostic value of the triglyceride glucose(TyG)index for the development of coronary heart disease(CHD)in elderly patients with type 2 diabetes mellitus(T2DM).Methods According to the results of coronary angiography,228 elderly patients with T2DM were divided into two groups of A(with CHD,149 cases)and C(without CHD,79 cases).The relevant clinical data were compared between the two groups.Multivariate logistic regression was used to analyze the risk factors for CHD in elderly patients with T2DM.The diagnostic value of TyG index for CHD in elderly patients with T2DM was evaluated using ROC curve.Results The proportion of hypertension,HbA1c,FBG,TG,TC,LDL-C,AST,Plt and TyG index in group A were higher than those in group C(P<0.05).Hypertension and higher AST and TyG index were the independent risk factors for CHD in elderly patients with T2DM(P<0.05).The area under the curve of TyG index in diagnosing the occurrence of CHD was 0.808[95%CI(0.748-0.867)](P<0.01).Taking 9.028 as the optimal cut-off value for the TyG index to diagnose the occurrence of CHD,the sensitivity and specificity were 64.6%and 81.9%,respectively.Conclusion TyG index has a diagnostic value for CHD in elderly patients with T2DM.

Type 2 diabetes mellitusCoronary heart diseaseTriglyceride glucose indexGeriatrics

刘欢、安静思

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121000 辽宁,锦州医科大学锦州市中心医院研究生培养基地

锦州市中心医院老年医学科

2型糖尿病 冠心病 三酰甘油葡萄糖指数 老年

2024

江苏医药
江苏省人民医院(南京医科大学第一附属医院)

江苏医药

影响因子:0.707
ISSN:0253-3685
年,卷(期):2024.50(8)