Application of carbon nanoparticles injection before and during operation in endoscopic radical thyroidectomy
Objective To investigate the application value of carbon nanoparticles injection before and during operation in endoscopic radical thyroidectomy.Methods The clinical data of 120 patients undergoing endoscopic radical thyroidectomy were retrospectively analyzed.The patients were divided into two groups.Group A(98 cases)received ultrasound-guided injection of carbon nanoparticles before operation and group B(22 cases)was injected with carbon nanoparticles during operation.The central regional lymph node(CLN)dissection,metastasis and postoperative complications were compared between the two groups.Results There was no statistical difference in clinical data between the two groups(P>0.05).The number of CLN dissection[6.00(3.75,8.00)pieces vs.3.00(1.75,6.00)pieces]and the number of CLN metastasis[1.00(0,3.00)pieces vs.0(0,0.25)pieces]were more in group A than those in group B(P<0.05).The metastasis rate was higher in group A than that in group B(51.0%vs.22.7%)(P<0.05).No bleeding,hoarseness or cough after drinking water happened in two groups after operation.Conclusion Compared with injection of carbon nanoparticles during operation,ultrasound-guided injection of carbon nanoparticles before operation is simple and convenient,can increase the number of CLN dissection and metastasis rate,and does not increase the postoperative complications.