Value of the ratio of serum lactate to serum albumin combined with sequential organ failure assessment score in predicting inhospital death of patients with sepsis
Objective To explore the value of the ratio of serum lactate to serum albumin(LAR)combined with sequential organ failure assessment(SOFA)score in predicting inhospital death of the patients with sepsis.Methods According to the 30-day inhospital death,198 patients with sepsis were divided into two groups of A(inhospital death,51 cases)and B(survial and improved,147 cases).The clinical data and relevant laboratory indicators of the two groups were compared.The risk factors for inhospital death of the patients with sepsis were analyzed.The correlation between LAR and SOFA score was analyzed.ROC curve was drawn to evaluate the predictive efficacy of LAR and SOFA score alone and in combination for inhospital death of the patients with sepsis.Results Compared with group B,age was older,heart rate,respiration rate,SOFA score,BUN,SCr,procalcitonin,blood potassium and LAR were increased,while body temperature and Plt were decreased in group A(P<0.05 or P<0.01).Increased age,LAR and SOFA score were the independent risk factors for inhospital death of sepsis patients(P<0.05 or P<0.01).LAR was positively correlated with SOFA score in the patients with sepsis(r=0.614,P<0.01).AUC of combined use of LAR and SOFA score in predicting inhospital death of the patients with sepsis was 0.842 with the sensitivity of 82.4%and the specificity of 74.1%,respectively.Conclusion LAR combined with SOFA score has a higher predictive value for inhospital death of the patients with sepsis.
Ratio of serum lactate to serum albuminSequential organ failure assessment scoreSepsis