Objective To explore the predictive value of global registry of acute coronary events(GRACE)score combined with leuko-glycemic index(LGI)for major adverse cardiovascular events(MACE)occurrence in acute myocardial infarction(AMI)patients within 2 years after percutaneous coronary intervention(PCI).Methods According to 2-year follow-up,256 patients with AMI undergoing PCI were divided into two groups of A(with MACE,75 cases)and B(without MACE,181 cases).Clinical and laboratory indicators of the two groups were compared,the risk factors for MACE occurrence in AMI patients within 2 years after PCI were analyzed,and ROC curves were dawn to evaluate predictive efficacy of GRACE score,LGI alone and in combination in MACE occurrence in AMI patients within 2 years after PCI.Results Compared with group B,group A had lower male proportion and left ventricular ejection fraction(LVEF)(P＜0.05 or P＜0.01).The age,proportion of Killip grade＞grade Ⅰ,GRACE score,cardiac troponin Ⅰ(cTnⅠ),brain natriuretic peptide(BNP),neutrophil to lymphocyte ratio(NLR)and LGI were all increased in group A than those in group B(P＜0.05 or P＜0.01).Elevated GRACE score,cTnⅠ,BNP and LGI and decreased LVEF were the independent risk factors for MACE occurrence in AMI patients within 2 years after PCI(P＜0.01).The AUC for combined use of GRACE score and LGI in predicting MACE occurrence in AMI patients within 2 years after PCI was 0.900,with the sensitivity of 81.3％and specificity of 85.1％.Conclusion Elevated GRACE score and LGI are the independent risk factors for MACE occurrence in AMI patients within 2 years after PCI.Combined use of GRACE score and LGI in predicting MACE occurrence has better predictive value.
Acute myocardial infarctionMajor adverse cardiovascular eventsGlobal registry of acute coronary eventsLeuko-glycemic index
NETL
NSTL
万方数据
