Application effect of different sedation methods in patients undergoing painless bronchoscopy
Objective To observe the efficacy of different sedation methods in the patients undergoing painless bronchoscopy.Methods A total of 120 patients undergoing painless bronchoscopy were randomly divided into three groups with 40 cases each.Anesthesia was induced with butorphanol 15 μg/kg plus propofol 2 mg/kg in group A,with midazolam 0.05 mg/kg plus butorphanol 15 μg/kg and propofol 2 mg/kg in group B,and with pumping dexmedetomidine 0.75 μg/kg for 5 minutes and intravenous injection of butorphanol 15 μg/kg and propofol 2 mg/kg then after.The general information,the times of lossing consciousness and postoperative awakening were recorded.MAP,HR,RR and SpO2 were compared among the three groups during anesthesia.The anesthetic efficacy and the occurrence of adverse reactions were evaluated.Results The time for loss of consciousness in group C was longer than that in groups of A and B(P＜0.05).The postoperative awakening time in group B was longer than that in group A and group C(P＜0.05).Compared with groups of A and B,the fluctuations of MAP,HR,RR and SpO2 during anesthesia in group C were smaller(P＜0.05).The excellent and good rate of anesthesia efficacy in group C was better than that in groups of A and B(P＜0.05),which was not statistically different between groups of A and B(P＞0.05).The incidence of cough and respiratory depression in groups of A and B was higher than that in group C(P＜0.05),which was not statistically different between groups of A and B(P＞0.05).Conclusion In the patients undergoing painless bronchoscopy,dexmedetomidine combined with butorphanol and propofol can provide the satisfactory anesthesia efficacy with a better stable vital signs and less adverse reactions.
万方数据
维普
