不同镇静方式在无痛支气管镜检查患者的应用效果
Application effect of different sedation methods in patients undergoing painless bronchoscopy
刘珂 1沈棋洪 1姚益冰 1陈燕君 1来岚 1陆雅萍1
作者信息
- 1. 314000 浙江,嘉兴市第一医院麻醉科
- 折叠
摘要
目的 观察不同镇静方式在无痛支气管镜检查患者的应用效果.方法 120例拟行无痛支气管镜检查患者随机分为三组,每组40例.麻醉诱导A组予静脉推注布托啡诺15 μg/kg+丙泊酚2 mg/kg;B组予静脉推注咪达唑仑0.05 mg/kg+布托啡诺15 μg/kg+丙泊酚2 mg/kg;C组予右美托咪定0.75 μg/kg泵注5 min后,静脉推注布托啡诺15 μg/kg+丙泊酚2 mg/kg.记录三组患者一般资料、意识丧失时间和术后可唤醒时间,比较三组患者围检查期MAP、HR、RR及SpO2变化,并评估三组麻醉效果及不良反应发生情况.结果 C组意识丧失时间长于A组和B组(P＜0.05).B组术后可唤醒时间长于A组和C组(P＜0.05).与A组和B组比较,C组围检查期MAP、HR、RR及SpO2的波动较小(P＜0.05).C组麻醉效果优良率高于A组和B组(P＜0.05);而A组与B组优良率比较差异无统计学意义(P＞0.05).A组和B组呛咳、呼吸抑制发生率均高于C组(P＜0.05);而A组与B组呛咳、呼吸抑制发生率比较差异无统计学意义(P＞0.05).结论 在接受无痛支气管镜检查的患者中,右美托咪定联合布托啡诺、丙泊酚可提供令人满意的麻醉效果,生命体征较稳定,不良反应较少.
Abstract
Objective To observe the efficacy of different sedation methods in the patients undergoing painless bronchoscopy.Methods A total of 120 patients undergoing painless bronchoscopy were randomly divided into three groups with 40 cases each.Anesthesia was induced with butorphanol 15 μg/kg plus propofol 2 mg/kg in group A,with midazolam 0.05 mg/kg plus butorphanol 15 μg/kg and propofol 2 mg/kg in group B,and with pumping dexmedetomidine 0.75 μg/kg for 5 minutes and intravenous injection of butorphanol 15 μg/kg and propofol 2 mg/kg then after.The general information,the times of lossing consciousness and postoperative awakening were recorded.MAP,HR,RR and SpO2 were compared among the three groups during anesthesia.The anesthetic efficacy and the occurrence of adverse reactions were evaluated.Results The time for loss of consciousness in group C was longer than that in groups of A and B(P＜0.05).The postoperative awakening time in group B was longer than that in group A and group C(P＜0.05).Compared with groups of A and B,the fluctuations of MAP,HR,RR and SpO2 during anesthesia in group C were smaller(P＜0.05).The excellent and good rate of anesthesia efficacy in group C was better than that in groups of A and B(P＜0.05),which was not statistically different between groups of A and B(P＞0.05).The incidence of cough and respiratory depression in groups of A and B was higher than that in group C(P＜0.05),which was not statistically different between groups of A and B(P＞0.05).Conclusion In the patients undergoing painless bronchoscopy,dexmedetomidine combined with butorphanol and propofol can provide the satisfactory anesthesia efficacy with a better stable vital signs and less adverse reactions.
关键词
无痛支气管镜检查/镇静/咪达唑仑/右美托咪定/丙泊酚/布托啡诺Key words
Painless bronchoscopy/Sedation/Midazolam/Dexmedetomidine/Propofol/Butorphanol引用本文复制引用
基金项目
嘉兴市公益性研究计划项目(2021AD30152)
出版年
2024
NETL
NSTL
维普
万方数据