Analysis of clinical characteristics of patients with ankylosing spondylitis combined with coronary heart disease
Objective To analyze the clinical characteristics of the patients with ankylosing spondylitis(AS)combined with coronary heart disease(CHD).Methods The differences in general data,laboratory indexes and echocardiograms were compared between the patients with AS combined with CHD(group A,36 cases)and the patients only with CHD(group B,36 cases).Results The age of CHD onset in group A was significantly younger than that in group B(P＜0.05).The levels of C-reactive protein,D-dimer and fibrinogen in group A were significantly higher than those in group B(P＜0.05).The end-diastolic internal diameter of the left ventricle in group A was significantly smaller than that in group B(P＜0.05).Conclusion Compared with the patients with CHD alone,the patients with AS combined with CHD have younger age of CHD onset,higher degree of inflammatory response,and more pronounced abnormalities in coagulation-fibrinolytic system and decreased cardiac function.
万方数据
维普
