首页|CMC-MMA-AA纳米乳液的制备及其抗蛋白质吸附性能的研究

CMC-MMA-AA纳米乳液的制备及其抗蛋白质吸附性能的研究

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本文以羧甲基纤维素(CMC)为乳化剂,甲基丙烯酸甲酯(MMA)和丙烯酸(AA)为单体,H2O2+Fe2+为引发剂,采用乳液聚合技术制备了 CMC-MMA-AA纳米乳液.通过SEM、DLS、TG、IR对乳胶粒的理化性质进行表征,并采用BLI、SDS-PAGE等方法验证纳米粒子的抗蛋白质吸附性能.结果表明:使用羧甲基纤维素包被后的聚甲基丙烯酸甲酯-丙烯酸纳米粒子粒径大小均一,粒径分布较窄,且具备良好的抗蛋白质吸附性能.
Study on Preparation of CMC-MMA-AA Nanoemulsion and Its Anti-protein Adsorption Properties
In this study,a nanoemulsion(CMC-MMA-AA)was prepared using emulsion polymerization technology,employing carboxymethyl cellulose(CMC)as the emulsifier,and methyl methacrylate(MMA)and acrylic acid(AA)as monomers,with H2O2+Fe2+serving as initiators.The physicochemical properties of the latex particles were characterized through SEM,DLS,TG,and IR analyses,while the resistance to protein adsorption of the nanoparticles was validated using BLI,SDS-PAGE,and other techniques.The findings revealed that the carboxymethyl cellulose-coated poly(methyl methacrylate-acrylic acid)nanoparticles exhibited uniform particle size,a narrow particle size distribution,and outstanding resistance to protein adsorption.

Methyl MethacrylateCarboxymethylcelluloseEmulsion PolymerizationAnti-protein adsorption

罗欣昕、王甦晓

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湖北大学化学化工学院,武汉 430062

甲基丙烯酸甲酯 羧甲基纤维素 乳液聚合 抗蛋白质吸附

2024

胶体与聚合物
湖北大学

胶体与聚合物

影响因子:0.259
ISSN:1009-1815
年,卷(期):2024.42(1)
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