Preparation and Antibacterial Properties of"Sandwich"Structured Silver@Poly dopamine@Silver Hollow Microspheres
In this study,sulfonated polystyrene(SPS)microspheres were employed as templates,leveraging the stabilizing and reducing properties of polyvinylpyrrolidone(PVP)towards silver ammine ions([Ag(NH3)2]+)to deposit Ag nanoparticles on the microsphere surfaces,forming SPS@Ag composite microspheres.Subsequently,under mildly alkaline conditions,a layer of polydopamine(PDA)was bio-inspiredly grafted onto the composite microsphere surfaces through dopamine modification.Utilizing the reactive groups on the PDA shell,[Ag(NH3)2]+ions were in-situ reduced to Ag nanoparticles,which were securely anchored onto the PDA shell.By selectively dissolving the SPS microspheres with a solvent,hollow microspheres with a"sandwich"structure of silver@polydopamine@silver(Ag@PDA@Ag)were ultimately fabricated.In antibacterial performance evaluations,the Ag@PDA@Ag hollow microspheres displayed remarkable antibacterial activity and sustained efficacy against both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus.This research not only introduces a novel strategy for the design of antimicrobial materials but also offers a potent candidate material for combating a broad spectrum of bacterial infections in practical applications.
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