基于罗丹明衍生物的次氯酸响应型荧光探针的构建及其性能研究
Construction and Performance Study of Hypochlorous Acid-Responsive Fluorescent Probes Based on Rhodamine Derivatives
满若琳 1张君美 1成奋民 1郝远强 1陈述 1曾荣今 1张培盛1
作者信息
- 1. 湖南科技大学化学化工学院,湖南湘潭 411201
- 折叠
摘要
以罗丹明B酰肼为基本骨架,设计合成了一种能够对次氯酸(HClO)进行特异性检测的小分子荧光探针(RBHD).该探针本身呈现出丹磺酰胺的蓝绿色荧光,当HClO存在时,探针分子中的亚氨基被氧化,进一步水解释放出罗丹明B基团,体系荧光由蓝绿色变为橙红色,实现了对HClO的特异性检测.此外,该探针能够对HClO实现快速响应(响应时间10 s),表现出高灵敏度和优良的选择性,并且成功应用于环境水中HClO的检测.
Abstract
A small molecule fluorescent probe(RBHD)was designed and synthesized using rhodamine B hydrazide as the basic skeleton,which can specifically detect hypochlorous acid(HClO).The probe itself shows the blue-green fluorescence of dansulfonamide.The imine in the probe molecule is oxidized in the presence of HClO,and further hydrolysis releases the rhodamine B group.The fluorescence of the system is changed from blue-green to orange-red,which realizes the specific detection of HClO.In addition,the probe was able to achieve a rapid response to HClO(response time 10 s),showing high sensitivity and excellent selectivity,and was successfully applied to the detection of HClO in environmental water.
关键词
荧光探针/罗丹明B/丹磺酰胺/次氯酸Key words
Fluorescent Probe/Rhodamine B/Dansulfamide/Hypochlorous Acid引用本文复制引用
出版年
2024
NETL
NSTL
万方数据