Hypoglycemic activities of proteins and enzymatic-hydrolyzed products from 12 species of edible fungi
Edible fungi can provide a variety of nutrients necessary for human bodies,including lots of proteins,polysaccharides and other active substances.Small molecular peptides produced by protease hydrolysis are important forms of protein activity.Protease-hydrolyzed peptides in edible fungi have received extensive attention due to their natural,safe,and good hypoglycemic effect.In this study,the proteins of 12 species of common edible fungi were selected as the research objects,and were extracted by ammonium sulfate precipitation method.The obtained proteins were then enzymatically hydrolyzed by alkaline protease.The inhibition rate of α-amylase and α-glucosidase were used as the screening indexes.The results showed that the protease hydrolysates of Hericium erinaceus had the best effect on the inhibition of α-amylase and α-glucosidase.The inhibition rate of α-amylase was(65.70±0.33)%,and that of α-glucosidase was(69.25±0.27)%,suggesting that H.erinaceus may have good hypoglycemic activity.The hydrophobic and alkaline amino acids contained in the enzymatic-hydrolyzed peptides of H.erinaceus may be important factors for the hypoglycemic effect.
万方数据
维普
