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松杉灵芝种质资源利用与药用活性成分研究进展

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松杉灵芝作为一种重要的药用真菌,具有丰富的种质资源和多种生物活性物质.本文回顾了松杉灵芝的种质资源和生物活性物质方面的研究进展.松杉灵芝的自然分布主要集中在中国东北地区,其人工栽培主要采用段木栽培模式,以落叶松木和蒙古栎木为培养基原料,在林下仿生栽培、林下野生栽培和棚室栽培等模式下取得了显著成果;松杉灵芝富含多糖、萜类和甾醇等活性成分,其中多糖和三萜是松杉灵芝的重要活性成分,已有研究表明其能够增强机体免疫功能、抑制肿瘤细胞生长和转移,并对心脑血管系统具有保护作用.对其进一步的研究应关注活性成分的提取与纯化、药理机制的探索以及人工栽培技术的改进,以实现其更广泛的开发利用.
Research progress of germplasm resource utilization and medicinal active components of Ganoderma tsugae
Ganoderma tsugae,a significant medicinal fungus,has abundant germplasm resources and various bioactive substances,having a long collection and utilization history in China.This paper is the research progress of the germplasm resources and bioactive substances of G.tsugae.G.tsugae is mainly distributed in the northeast region of China.Its artificial cultivation mainly adopts cut-log cultivation mode,using the wood of larch and Mongolian oak as culture medium.Significant achievements have been made in biomimetic cultivation under forest,wild cultivation under forest,greenhouse cultivation and other modes.G.tsugae is rich in active ingredients such as polysaccharides,terpenoids,and sterols,among them polysaccharides and triterpenes are important.Previous studies have shown that they can enhance the body's immune function,inhibit tumor cell growth and metastasis,and have protective effects on the cardiovascular and cerebrovascular systems.Further research should focus on the extraction and purification of active ingredients,exploration of pharmacological mechanisms,and improvement of artificial cultivation techniques in order to achieve their more wide-ranging development and utilization.

Ganoderma tsugaegermplasm resourcesbioactive substancesmedicinal fungiantitumorimmune regulation

代瑞、李金涛、刘成伟、闫梅霞

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东北林业大学生命科学学院,黑龙江哈尔滨 150040

中国农业科学院特产研究所,吉林长春 130112

松杉灵芝 种质资源 生物活性物质 药用真菌 抗肿瘤 免疫调节

2024

菌物学报
中科院微生物研究所 中国菌物学会

菌物学报

CSTPCD北大核心
影响因子:1.187
ISSN:1672-6472
年,卷(期):2024.43(12)