Pirimicarb was synthesized from 5,6-dimethyl-2-dimethylamino-4-hydroxy pyrimidine and dimethylcarbamyl chloride in the presence of acid-binding agent.The effects of the rate of hydrolysis of dimethylcarbamyl chloride,the solvent,the catalyst,and the ratio of raw materials were investigated.The title compound was obtained in 98％ yield (based on 5,6-dimethyl-2-dimethylamino-4-hydroxy pyrimidine) with 98％ purity under the optimized conditions.
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