To conduct experimental research on freeze concentration,cefradine centrifuge mother liquor was used as the research object.The effects of factors incuding freezing device,freezing temperature,pH value,freezing time,and stirring mode on the freezing process were studied.The results showed that using an internal scraping type freeze concentration device for freeze concentration,at a freezing temperature of-8 ℃,a freezing time of 4 hours,and a stirring speed of 150 r/min,the better freeze concentration effect was achieved,and the extraction yield of cefradine was 88.7％.
维普
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