As raw material,cyclical acid was esterified with methanol under the catalysis of solid acid to get methyl salicylate,and then the methyl salicylate was ammoniated with ammonia in methanol to synthesize salicylamide.The optimized reaction conditions were as following:in esterfication reaction,the mass ratio of strong acid resins to salicylic acid was 0.35∶1.00,the molar ratio of methanol to salicylic acid was 10∶1,and the reaction temperature was 135 ℃.After catalysis for 10 cycles of solid acid,the average yield of methyl salicylate was 81.1% and the content was 99.2% .In ammonification reaction,the molar ratio of ammonia to methyl salicylate was 4.0∶1.0,the mass ratio of methanol to methyl salicylate was 1.0∶1.0,the mass ratio of sodium sulfite to methyl salicylate was 0.002∶1.000,and the reaction temperature was 60 ℃,with the yield and the content of salicylamide as 99.3% and 99.1% ,respectively.This method has the advantages of high purity,high yield,less wastewater and is environmentally friendly.
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