Study on the Mixing Process of Cefepime Hydrochloride and Arginine Powder
The aim of the study is to optimize the mixing process of cefepime hydrochloride arginine powder.Using conditions such as crystallization temperature,mesh size,and mixing ratio as examination factors,and the particle size of cefepime hydrochloride as examination indicators,explore the optimal mixing conditions.The optimal mixing process is determined as follows:crystallization temperature of 9.0 ℃,grinding mesh aperture of 1.0 mm,mixing ratio of 1∶0.590,mixing speed of 8.1 r/min,mixing time of 45 minutes,and vibration strength of 65％.The product obtained by this process is easy to package and suitable for industrial production.
NETL
NSTL
万方数据
维普
