Research on the Extraction Process of Lycium barbarum with Multi-index Response Surface Optimization
Lycium barbarum is rich in Lycium barbarum polysaccharide(LBP)and Lycium barbarum flavones,both of which possess significant medicinal value.The effects of extraction method,extraction time,solid-liquid ratio,extraction times and extraction temperature and snaking time were studied by single factor test.Based on the results of single-factor experiments,three significant effects were selected to optimize the extraction technology of LBP and Lycium barbarum flavones using Box-Behnken experimental design.The optimal extraction conditions are determined through these experimental results:by the heating and reflux method,soaking for 1.0 h,55 minutes of extraction time,a solid-liquid ratio of 1∶12(g∶mL),extraction temperature of 81 ℃,and extracting twice.Under these conditions,the extraction rates of LBP and Lycium barbarum flavones reached 45.36％and 0.29％,respectively.The method has high extraction rate,good reproducibility,high efficiency and environmental sustainability,providing a valuable reference for the extraction method of LBP and Lycium barbarum flavones from Lycium barbarum.
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万方数据
维普
