Identification and Characterization of an Impurity in the Mother Liquor of p-Hydroxyphenylglycine
An impurity in the mother liquor of p-hydroxyphenylglycine was prepared by extraction,dissociation,crystallization and filtration.The effects of the extraction agent,extraction conditions and crystallization time on the extraction results were investigated,and the optimal extraction process was determined.The HPLC purity of the product was 99.1％(HPLC).The impurity was identified as bis(4-hydroxyphenyl)acetic acid by MS,1H NMR,13C NMR and 2D NMR.
p-hydroxybenzylglycinebis(4-hydroxyphenyl)acetic acidextraction process
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