A Study on the Chemical Constituents From Leaves of Rosa laevigata Michx.
The 75%ethanol extract of the leaves of Rosa laevigata Michx.were separated and purified by modern chromatography separation technologies such as macroporous resin chromatography,ODS chromatography,gel chromatography,etc.The identification of chemical structure was based on physical and chemical properties as well as spectral data.Eight compounds were obtained:3-oxo-α-ionol-β-D-glucopyranoside(1),7,8-dihyd-3-oxo-α-ionol-β-D-glucopyranoside(2),9-hydroxymengastigman-5-en-4-one-O-primeveroside(3),4-oxo-β-ionol-β-D-glucopyranoside(4),7,8-dihyd-4-oxo-β-ionol-β-D-glucopyranoside(5),methyl phloroglucinol-β-D-glucopyranoside(6),ethyl gallate(7),p-hydroxyl ethyl cinnamate(8).Compounds 1、2、3、5 were isolated from genus Rosa for the first time.Studying the chemical composition of the leaves of Rosa laevigata Michx.lays the foundation for future research on its pharmacological mechanism.
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