Clinical Effect and Evaluation of Bushen Qingre Mixture in Treating Children with Peripheral Precocious Puberty
Objective:To explore the clinical efficacy and safety of Bushen Qingre mixture in the treatment of children with peripheral precocious puberty.Methods:A total of 40 children with pe-ripheral precocious puberty in our hospital were selected and treated with Bushen Qingre mixture.The height,weight,uterine volume,ovarian volume,estrogen levels,breast stage and adverse e-vents were observed.Results:The height of children gradually increased after 3 and 6 months of treatment with Bushen Qingre mixture,but some children did not increase at 9 months,and contin-ued to increase at 12 months.After 3 to 6 months of treatment,the weight increased slowly.After 3 to 12 months of treatment,uterine volume and ovarian volume increased slowly.The level of estradi-ol decreased rapidly after 3 months of treatment,but increased again after 6 to 12 months of treat-ment in some children.After treatment with Bushen Qingre mixture,the breast stage of the child re-mained unchanged at B2-B3.All children had no adverse reactions during oral administration of Bushen Qingre mixture.Conclusion:Bushen Qingre mixture is effective in the treatment of children with peripheral precocious puberty,and has less adverse reactions.It is worthy of application.
国家科技期刊平台
NSTL
万方数据
维普
