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茯苓中24种无机元素的测定及健康风险评估

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为评价茯苓的品质和重金属污染现状,并为建立茯苓质量评价体系提供参考,研究采用微波消解-ICP-MS法测定了云南、安徽和湖北等不同省份41份的茯苓样品中Li、Be、Ti、V、Cr、Fe、Co、Ni、Cu等24种无机元素的含量,使用单因子污染指数法(Pi)及内梅罗综合指数法(P综)对其中的Pb、Cd、Cu、As、Hg等5种有害重金属元素进行安全性评价和健康风险评估.结果表明,茯苓检测样品中Fe的含量最高(33.49 mg·kg-1),其次是Cu(1.56 mg·kg-1)、Ti(1.208 mg·kg-1)、Ba(1.007 mg·kg-1)、Rb(0.998 mg·kg-1).41份茯苓样品的Pi与P综均小于0.7,处于安全水平,以靶标危害系数(THQ)和致癌风险参数(CR)为指标的健康风险评估模型表明长期以茯苓入药时,其重金属及有害元素含量不会对暴露人群造成显著的健康影响,且不存在潜在的致癌风险.
Determination of 24 inorganic elements in Poria cocos and health risk assessment
To evaluate the quality and heavy metal pollution status of Poria cocos,it was provided a reference for establishing the quality evaluation system of P.cocos.The content of 24 elements,including Li,Be,Ti,V,Cr,Fe,Co,Ni,Cu,etc.,in 41 samples of P.cocos from different Provinces such as Yunnan,Anhui,and Hubei was determined using microwave digestion ICP-MS.The safety and health risk assessment of five heavy metals,Pb,Cd,Cu,As,Hg,and harmful elements were conducted using single factor pollution index(Pi)and Nemero comprehensive index(Pc)methods.The results showed that the content of Fe in P.cocos was the highest(33.49 mg·kg-1),followed by Cu(1.56 mg·kg-1),Ti(1.208 mg·kg-1),Ba(1.007 mg·kg-1),and Rb(0.998 mg·kg-1).The comprehensive values of Pi and Pc in 41 samples of P.cocos were both less than 0.7,which were at a safe level.The health risk assessment model with target hazard coefficient(THQ)and carcinogenic risk(CR)as indicators showed that when P.cocos was used for a long time,its heavy metal and harmful element content will not have significant health effects on the exposed population,and there was no potential carcinogenic risk.

Poria cocosheavy metals and harmful elementsinductively coupled plasmahealth risk assessment

李道成、朱灵芝、王裕成、张香、洪家顺

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江西省道地药材质量评价研究中心,江西南昌 330029

江西省林业科学院,江西南昌 330013

茯苓 重金属及有害元素 电感耦合等离子体 健康风险评估

赣江新区科技计划项目江西省省重点研发计划项目

赣新管创发[2020]26号20224BBG72001

2024

南方林业科学
江西省林业科学院,江西省林学会

南方林业科学

影响因子:0.56
ISSN:1006-2505
年,卷(期):2024.52(3)