Based on the Romax software,this paper focus on the modle 6212 deep groove ball bearings,the regression model of deep groove ball bearing was established by quadratic regression universal rotation combination design method.Using the regres-sion equations and the method of weighting optimization,the dual-objective parameter optimized design of deep groove ball bear-ing was carried on,and the optimization results of the bearing is verified by simulation,it is found by contrast that the life and ra-dial stiffness of the simulation value and the predicted value is relatively close;The life and radial stiffness of the bearing decrease with the increase of the curvature coefficient of inner and outer ring groove.The interaction of the curvature coefficients fi and fe of the inner and outer rings on the radial stiffness of the bearing is generally greater than that on the life of the bearing,showing that the optimization model and the calculation method are correct,and it can be used to analyze and predict the life and radial stiffness of deep groove ball bearing.