Research on Porous Structure Design and Flow Field Characteristics of Bone Scaffold
The structure of the tissue engineering bone scaffold and its flow property directly affect the flow of nutrients and deposi-tion of cells.Based on topology optimization,the unit cell models under different porosity and scales were designed with the actual force of tibial fracture as the load.Computational fluid dynamics(CFD)method was used to numerically simulate the internal flow field characteristics of unit cells and constructed porous structures.The effects of model parameters on the velocity distribution and permeability of the internal flow field of each structure were analyzed.The results show that the unit cell and porous structure under different porosity and scale have good connectivity,and porosity is the main factor affecting flow velocity.The permeability of each structure increases with the increase of porosity and scale.Structures with larger porosity and scale show better fluid flow performance.The research results can provide support for the optimal design and application of the porous structure of bone scaf-folds.
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