In order to solve the flow problem caused by cementation damage at the cementation interface in the process of oil well re-sealing,a self-made experimental device for cementation interface sealing and numerical simulation method are adopted to study the key factors and mechanism of flow triggering at the cementation inter-face.The results show that:the shear damage at the cementing interface is the main cause of cementing interface sealing failure;the higher the interface cementing index(BI),the lower the interlayer pressure difference,the higher the horizontal principal stress,and the lower the damage at the cementing interface,the stronger the seal-ing ability of the cementing interface is.By weighting the influencing factors,it is found that cement ring cemen-tation strength and interlayer pressure difference are the key factors affecting the sealing ability of cementing in-terface.