A new method for the determination of acetaminophen by resonance light scattering enhancement-dual wavelength superposition method(ERLS-DWSM)was established.The effect of the optimized experi-mental conditions of acetaminophen-crystalline violet system on the intensity of resonance light scattering was investigated using a fluorescence spectrophotometer in pH 2.40 B-R buffer medium.The experimental results showed that the concentration of acetaminophen was linearly related to the scattering intensity(ΔIRLS)within the range of 0.05-0.40 mg/L,with a detection limit of 0.032 5 mg/L.The current method is consistent with the UV spectrophotometry for the determination of acetaminophen content.
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