Study on surface treatment and biological properties of porous titanium alloy by laser additive manufacturing
Titanium alloy is widely used in the field of orthopedic implants due to its high hardness,wear resistance,and good biocompatibility.However,the untreated surface of titanium alloy usually exhibits poor cell adhesion,which is not conducive to bone integration.To stimulate the biological activity of titanium alloy,its surface needs to be modified.In this study,porous Ti6Al4V alloy prepared by laser powder bed fusion(LPBF)was modified through alkali heat treatment(AHT)to enhance its biological activity.The study investigated the impact of alkali solution concentration and treatment time on the surface morphology of titanium alloy.The biocompatibility of the surface-modified samples was also tested.The results showed that the sample underwent pretreatment through acid washing,followed by soaking in a 7 mol/L NaOH solution at 60℃for 1 h.After high-temperature sintering,a well-formed and evenly distributed nano-reticulated sodium titanate coating was formed on the sample's surface.Finally,the sample was soaked in simulated body fluid for 10 d to form apatite coating.Following direct contact,hBMSC were inoculated onto the sample and cultured for 48 h.The relative cell activity of the sample significantly improved after alkali heat treatment and simulated body fluid immersion compared to the untreated sample.
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