摘要
目的 探讨江西省儿童单纯性血尿的病理类型.方法 对159例单纯性血尿的患儿进行肾组织活检,并行光学显微镜、电子显微镜和免疫荧光检查.结果 单纯性血尿肾脏病理类型最常见的依次为轻度系膜增生性肾小球肾炎69例(43.4%)、IgA肾病36例(22.6%)和局灶节段性肾小球肾炎24例(15.1%),其次为轻微病变17例(10.7%)、局灶节段性肾小球硬化4例(2.5%)、微小病变1例(0.6%)、膜性肾病1例(0.6%)、新月体肾炎1例(0.6%)、膜增殖性肾炎1例(0.6%)和IgM肾病1例(0.6%).结论 单纯性血尿最常见的病理类型是轻度系膜增生性肾小球肾炎,其次是IgA肾病及局灶阶段性肾小球肾炎.
Abstract
Objective To investigate the pathological types of isolated hematuria in children in Jiangxi province. Methods Renal biopsy was performed in 159 children diagnosed with isolated hematuria. All biopsies were examined by light microscope, electron microscope and immunofluoresence. Results The most common pathological types were mesangial proliferation glomerulonephritis (69 cases,43.4%),IgA nephropathy (36 cases,22.6%) and focal segmental glomerulonephritis (24 cases,15.1%) ,followed by minor glomerular abnormalities (17 cases, 10.7%), focal segmental glomerulosclerosis (4 cases, 2. 5%), minimal change nephrotic syndrome (1 case,0.6%), membranous glomerulopathy ( 1 case, 0.6% ), crescentic glomerulonephritis ( 1 case,0.6 % ), membranoproliferative glomerulonephritis (1 case, 0.6 % ), and IgM nephropathy (1 case,0.6%). Conclusion Mesangial proliferation glomerulonephritis is the most common pathplogical changes in isolated hematuria, followed by IgA nephropathy and focal segmental glomerulonephritis.