首页|不同路径植入中心静脉导管安全有效性的网状Meta分析

不同路径植入中心静脉导管安全有效性的网状Meta分析

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目的 采用网状Meta分析比较经颈内静脉、锁骨下静脉和腋静脉植入中心静脉导管(central venous cathe-ter,CVC)的安全性及有效性,以期为临床选择中心静脉导管最佳穿刺路径提供证据支持.方法 系统检索中国知网、万方、维普中文科技期刊数据库、中国生物医学文献服务系统(CBM)、PubMed、Web of Science、Cochrane librar-y、Embase数据库,检索建库至2022年7月有CVC不同植入路径的已发表文献,采用Review Manager 5.3软件进行传统Meta分析和Stata 14.0软件进行网状Meta分析.结果 共纳入18篇随机对照试验,包含6746例研究对象.Meta分析显示,3种路径中经腋静脉植入CVC首次穿刺成功率优于颈锁骨下静脉[RR(95%CI):0.88(0.84~0.91)]、经腋静脉植入CVC总体并发症发生率低于经锁骨下静脉植入[RR(95%CI):1.90(1.23~2.92)],但高于经颈内静脉植入CVC[RR(95%CI):1.76(1.35~2.30)],差异具有统计学意义(P<0.05);锁骨下静脉组误穿动脉发生率高于腋静脉组[RR(95%CI):2.36(1.02~5.45)],气胸发生率高于腋静脉组[RR(95%CI):2.36(1.03~5.39)]和颈内静脉组[RR(95%CI):2.34(1.14~4.80)],导管相关感染发生率颈内静脉组高于锁骨下静脉组[RR(95%CI):0.34(0.16~0.69)],差异均具有统计学意义(P<0.05).结论 经腋静脉植入CVC在首次穿刺成功率和并发症发生率比较中有优势,推荐临床CVC植入首选腋静脉路径,但仍应充分考虑患者情况,个体化选择最优路径植入 CVC.
Network Meta-analysis of the Safety and Efficacy of Different Routes of Implanting Central Venous Catheters
Objective To compare the safety and efficacy of central venous catheter(CVC)im-plantation via the internal jugular vein,subclavian vein,and axillary vein through network meta-a-nalysis,and to provide evidence-based support for the clinical selection of the optimal route of central venous catheter puncture.Methods Chinese and English databases,including China Na-tional Knowledge Infrastructure(CNKI),Wanfang Data,Wipu,China Biomedical Literature,PubMed,Web of Science and Cochrane Library,Cochrane library and Embase,were systematically searched;literature on different implantation routes of central venous catheters published as of 2022 were searched;Review Manager 5.3 software was used for traditional Meta-analysis and Sta-ta 14.0 software for network meta-analysis.Results A total of 18 randomized controlled trials with 6746 subjects were included.Meta-analysis showed that the three routes were statistically significant in the comparison of catheter placement complications and first puncture success rate(P<0.05).The incidence of artery mispenetration was higher in the subclavian vein group than in the axillary vein group[RR(95%CI):2.36(1.02,5.45)],the incidence of pneumothorax was higher than that in the axillary vein group[RR(95%CI):2.36(1.03,5.39)]and the internal jugu-lar vein group[RR(95%CI):2.34(1.14,4.80)],and the incidence of catheter-related infection in the internal jugular vein group was higher than in the subclavian vein group[RR(95%CI):0.34(0.16,0.69)],all of which were statistically significant(P<0.05).Conclusion CVC implantation via axillary vein can have advantages in the comparison of first puncture success rate and compli-cation rate,and the axillary vein route can be preferred for clinical CVC implantation,but the pa-tient's condition should be fully considered and the optimal route should be selected for implanta-tion of CVC in an individualized manner.

central venous catheterinternal jugular veinsubclavian veinaxillary veinNetwork meta-analysis

冯琦凡、涂发妹、吴季敏、张永慧、刘萍萍、赵春霞、刘佳晨

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南昌大学护理学院,南昌 330006

南昌大学第一附属医院护理部,南昌 330006

南昌大学第一附属医院肿瘤科,南昌 330006

中心静脉导管 颈内静脉 锁骨下静脉 腋静脉 网状Meta分析

2024

南昌大学学报(医学版)
南昌大学

南昌大学学报(医学版)

CSTPCD
影响因子:1.008
ISSN:2095-4727
年,卷(期):2024.64(2)
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