Xin-huang Tablet in Neck Swelling and Pain after Microwave Ablation of Thyroid Nodules
Objective To investigate the efficacy of Xin-huang tablets in the management of neck swelling and pain after microwave ablation(MWA)of thyroid nodules.Methods 150 patients with neck swelling and pain after MWA were randomly divided into the treatment group,the placebo group and the control group,50 cases in each group.The treatment group took 3 Xin-huang tablets,tid,orally for 3 d immediately after the operation;the placebo group took placebo(starch pill),3 tablets,tid,orally for 3 d immediately after the operation;and the control group did not take any oral medication after the operation.Postoperative neck swelling and neck pain were compared among the 3 groups.Results The neck pain scores of the treatment group at 12,24,48 and 72 h postoperatively were significantly reduced compared with those of the control group and the placebo group,and the differences were statistically significant(P＜0.01);the incidence of neck swelling at 48 and 72 h postoperatively in the treatment group was significantly reduced compared with those of the control group and the placebo group,and the differences were statistically significant(P＜0.01);the duration of neck pain and swelling at 72 h postoperatively in the treatment group was significantly shorter compared with those of the control group and the placebo group,and the differences were all statistically significant(P＜0.01).Conclusions Xin-huang tablet can reduce neck swelling and pain,and relieve discomforts for patients who have received MWA of thyroid nodules,and it can be clinically considered for the management of neck swelling and pain after MWA of thyroid nodules.
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