Chinese and Western Medicine Studies on the Prevention and Treatment of Renal Injury Caused by Trivalent Arsenic:a Systematic Review
Trivalent arsenic(ASⅢ)is commonly used in the management of acute promyelocytic leukemia(APL),with positive therapeutic outcomes,but its autotoxicity limits its clinical application.Serving as the main excretory organ for ASⅢ,the kidney is particularly susceptible to its nephrotoxic effects,which can result in significant structural and functional impairments.Nevertheless,the pathogenesis of kidney injury caused by ASⅢ has not been fully elucidated,and effective preventive and therapeutic strategies are lacking.This article provides a comprehensive review of research advances in the incidence and risk of the pathogenesis,prevention and treatment of nephrotoxicity associated with arsenic-induced renal injury.
trivalent arsenickidney injurypathogenesisprevention and treatment of Chinese and western medicine
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