The Predictive Value of Systemic Immune-inflammation Index and Serum Glucose-potassium Ratio in Elderly Patients with Delayed Encephalopathy after Carbon Monoxide Poisoning
Objective To investigate the predictive value of systemic immune-inflammation index and serum glucose-potassium ratio in elderly patients with delayed encephalopathy after carbon monoxide poisoning.Methods A retrospective analysis was conducted on the clinical data of 96 elderly patients(＞60 years old)with acute carbon monoxide poisoning admitted to the 908th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force from 2010 to 2023.Among them,38 patients developed delayed encephalopathy after carbon monoxide poisoning(Group A),and 58 patients did not(Group B).Data on red blood cell count,hemoglobin,white blood cell count,neutrophil count,lymphocyte count,platelet count,blood glucose,and blood potassium were collected from both groups of patients,and the systemic immune-inflammation index(SIII)and serum glucose-potassium ratio(G/K)were calculated.The predictive value of SIII and G/K for delayed encephalopathy after carbon monoxide poisoning was analyzed by calculating the area under the curve using the receiver operating characteristic curve.Results There were statistically significant differences in white blood cell count,neutrophil count,lymphocyte count,platelet count,SIII,blood glucose,and G/K between the 2 groups of patients(P＜0.05).The most effective predictor of delayed encephalopathy after carbon monoxide poisoning was the SIII value(AUC=0.859,cut-off value＞1 666.75,sensitivity=0.842,specificity=0.759),followed by the G/K value(AUC=0.797,cut-off value＞29.87,sensitivity=0.789,specificity=0.724).Conclusion The values of SIII and G/K are potential predictors of whether elderly patients will develop delayed encephalopathy after carbon monoxide poisoning,and the early acquisition of SIII and G/K values can assist clinicians in taking targeted intervention measures to prevent the occurrence of delayed encephalopathy after carbon monoxide poisoning.
carbon monoxide poisoningdelayed encephalopathysystemic immune inflammation indexglucose-potassium ratio
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