首页|序贯疗法治疗轻中度痤疮的疗效观察

序贯疗法治疗轻中度痤疮的疗效观察

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目的:观察序贯疗法(中药+果酸+火针)治疗轻中度痤疮的临床疗效以及对患者皮肤屏障的影响.方法:将86例临床诊断为轻中度痤疮的患者随机分为观察组和对照组,各43例.对照组给予中药+果酸治疗,观察组在不同阶段给予序贯疗法(中药+果酸+火针)治疗,其中火针疗法于果酸术后4~5 d进行,2周1次,均治疗4次,共8周.通过皮损积分、皮肤病生活质量指数量表(DLQI)评分、标准面部图像评价治疗效果,通过无创皮肤检测仪测试皮肤经皮水分丢失量、角质层含水量、pH值、表皮脂质含量,评价对皮肤屏障的影响.结果:治疗后,2 组痤疮皮损积分及DLQI评分均下降,且观察组优于对照组(P<0.05);治疗后观察组的总有效率(95.35%)优于对照组(74.42%),治疗结束3个月后观察组复发率(8.57%)低于对照组(23.81%),差异均具有统计学意义(P<0.05);治疗后,2 组皮肤屏障功能均改善,且观察组的各项指标均优于对照组(P<0.05).结论:序贯疗法治疗轻中度痤疮具有疗效显著、复发率低、促进皮肤屏障修复的特点,能够显著提高痤疮治疗的近期和远期效果.
Efficacy of Sequential Therapy in the Treatment of Mild to Moderate Acne
Objective:To observe the clinical efficacy of sequential therapy(traditional Chinese medicine + fruit acid + fire acupuncture)in the treatment of mild to moderate acne and its effect on the skin barrier of patients.Methods:A total of 86 patients with clinically diagnosed mild to moderate acne were randomly divided into observation group and control group,with 43 cases each.The control group was treated with traditional Chinese medicine + fruit acid,and the observation group was treated with sequential therapy(traditional Chinese medicine + fruit acid + fire acupuncture)at different stages,among which fire acupuncture was carried out 4~5 days after fruit acid surgery,once in 2 weeks,and 4 times in both cases,for a total of 8 weeks.The treatment effect was evaluated by lesion score,DLQI score and standard facial image,and the transdermal water loss,stratum corneum water content,pH value,and epidermal lipid content were tested by non-invasive skin detector to evaluate the impact on the skin barrier.Results:After treatment,the score of acne lesions and DLQI scores decreased in both groups,and the observation group was better than that of the control group(P<0.05).The overall effective rate of the observation group after treatment(95.35%)was better than that of the control group(74.42%),and the recurrence rate of the observation group(8.57%)after 3 months after the end of treatment was lower than that of the control group(23.81%),and the difference was statistically significant(P<0.05).After treatment,the skin barrier function of both groups improved,and the indicators of the observation group were better than those of the control group(P<0.05).Conclusion:Sequential therapy in the treatment of mild to moderate acne has the characteristics of significant efficacy,low recurrence rate and skin barrier repair,which can significantly improve the short-and long-term effects of acne treatment.

Sequential TherapyMild to Moderate AcneSkin Barrier

梁育、赵倩子、汤慧、郑晓蝶、沈丹丹

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江西省中医院皮肤科 南昌 330000

序贯疗法 轻中度痤疮 皮肤屏障

江西省中医药管理局科技计划项目

2022B703

2023

江西中医药大学学报
江西中医学院

江西中医药大学学报

影响因子:0.575
ISSN:2095-7785
年,卷(期):2023.35(6)
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