Research on the Pathological Mechanism and Material Basis of Endometriosis Based on the Theory of Blood Stasis
Endometriosis is a disease characterized by morphological diversity,extensive lesions,malignant biological behavior,etc.,which bring many difficulties to clinical treatment.By reviewing and sorting out related ancient and modern literature and based on the theory of blood stasis,the pathological mechanism of endometriosis was discussed in depth from the origin of disease name,pathogenesis,syndrome factors and biological basis.Results showed that"abdominal masses due to blood stasis"or"aggregation accumulation"is highly consistent with endometriosis.It is believed that"blood stasis obstructing the thoroughfare and conception vessel and the uterus"is the key pathogenesis of endometriosis.Qi stagnation,cold congealing,phlegm-dampness,Qi deficiency and kidney deficiency are precipitating factors or subsequent pathogenesis of blood stasis.Blood stasis is the basic syndrome of the disease.Cell proliferation or angiogenesis factors,tumor markers,vasoconstriction factors and some differential proteins are specifically related to the blood stasis syndrome of the disease.These may provide a basis for exploring the material basis of blood stasis syndrome in endometriosis.
EndometriosisTheory of Blood StasisSyndromeMaterial BasisMechanism
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