枇杷清肺饮加减治疗肺经风热型痤疮48例疗效观察
Observation on the Therapeutic Effect of Modified Pipa Qingfei Decoction in the Treatment of 48 Acne Cases of Lung Meridian Wind Heat Type
李桂云 1王雅乐 1许苗 1曾庆涛 1詹群璋 2黄海 2吴红彦1
作者信息
- 1. 上海中医药大学深圳医院 广东 深圳 518004
- 2. 广州中医药大学第一临床医学院 广州 510405
- 折叠
摘要
目的:观察枇杷清肺饮加减治疗肺经风热型痤疮的临床疗效.方法:选取 2021 年 7 月—2022 年 11 月上海中医药大学深圳医院内分泌科及吴红彦名中医门诊诊治的 96 例痤疮患者作为观察对象,采取实用型随机对照试验方法,将全部受试者随机分成 2 组,每组 48 例.观察组采用口服中药枇杷清肺饮加减治疗,对照组采用口服盐酸多西环素片治疗.比较 2 组治疗前、治疗 6 周后痤疮综合分级系统(GAGS)评分及临床疗效,同时进行为期 3 个月的随访.结果:2 组治疗 6 周后,GAGS评分均有降低,且观察组降低程度更明显,差异有统计学意义(P<0.05);2 组总有效率比较,观察组(97.92%)高于对照组(72.92%),差异有统计学意义(P<0.05);2 组复发率比较,观察组(10.42%)低于对照组(33.33%),差异有统计学意义(P<0.05).结论:枇杷清肺饮加减治疗肺经风热型痤疮疗效确切,且复发率低.
Abstract
Objective:To observe the clinical effect of Pipa Qingfei Decoction in treating acne of wind-heat type of lung.Methods:96 acne patients from department of endocrinology of luohu hospital of traditional Chinese medicine of shenzhen city and WU Hongyan outpatient clinic were selected by practical randomized controlled experiment.96 subjects were randomly divided into two groups with 48 cases in each group.Subjects in the treatment group received oral modified pipa Qingfei Decoction,and subjects in the control group received oral doxycycline hydrochloride tablets.The researchers will compare the Comprehensive Acne Grading System(CAGs)scores and clinical outcomes of the two groups of subjects in the 6 weeks before and after GAGS assessment,and will also follow up for 3 months.Results:After 6 weeks of treatment,GAGS score decreased in both groups,and the decrease was more obvious in the treatment group,with a significant difference(P<0.05),indicating that the improvement effect of the treatment group was better.The total effective rate was 97.92%in the treatment group and 72.92%in the control group,and the treatment group was more effective than the control group(P<0.05).The recurrence rate in the treatment group(10.42%)was lower than that in the control group(33.33%).Conclusion:The modified Pipa Qingfei Yin has a definite therapeutic effect on lung meridian wind heat type acne,and has a low recurrence rate.
关键词
枇杷清肺饮/痤疮/肺经风热证/痤疮综合分级系统/随机对照试验Key words
Pipa Qingfei Decoction/Acne/Lung Meridian Wind Heat Syndrome/Comprehensive Acne Grading System/Practical Randomized Controlled Trial引用本文复制引用
基金项目
广东省自然科学基金(2020A1515010217)
深圳市罗湖区软科学研究计划(LX20191212)
深圳市罗湖区软科学研究计划(LX20210101)
出版年
2024
国家科技期刊平台
NSTL
万方数据