Research Progress on the Mechanism of Electroacupuncture on Chondrocytes in Knee Osteoarthritis
Knee osteoarthritis is one of the common chronic joint diseases in middle-aged and elderly people in China.There are many treatment methods,among which electroacupuncture is widely used in clinic.Electroacupuncture can treat knee osteoarthritis by regulating the proliferation,differentiation and apoptosis of chondrocytes and inhibiting the degradation of cartilage matrix,but its specific mechanism has not been elucidated.In recent years,domestic and foreign literatures have shown that the formation,proliferation and apoptosis of knee articular chondrocytes are closely related to related inflammatory factors,signaling pathways,biomechanics,mitochondria and proteins.This paper reviews the mechanism of electroacupuncture on knee osteoarthritis chondrocytes in the above four aspects,so as to provide reference for further research in the future.
ElectroacupunctureKnee OsteoarthritisChondrocytesMechanism of ActionReview