Application and Consideration of Metagenomics Technology in the Study of TCM Syndromes
Metagenomics is a sequencing research technology that takes microbial communities as the research object.It collects and analyzes the characteristics of microbial community structure,system evolution,metabolic pathways,gene functions and other aspects by extracting genetic information of all microorganisms in a specific environment.It has been widely used in a variety of medical-related microbial research fields.Introducing metagenomics into the research of traditional Chinese medicine and effectively combining Chinese medicine with modem micro-technology that also emphasizes integrity can make up for the lack of microscopic indicators in the research process of Chinese medicine,and has a unique application prospect.TCM syndromes are the bridge between the basic theories of TCM and TCM clinics.Starting from the research methods of metagenomics and attempting to carry out modern qualitative and quantitative analysis,it can partially reveal the essence of TCM syndromes and make TCM syndromes more standardized and scientific.Metagenomics has the characteristics of integrity,dynamics,and environmental unity,which is very consistent with the general characteristics of"syndrome"in Chinese medicine.Therefore,research on the essence of TCM syndromes based on metagenomics technology not only has high feasibility,but also can bring new directions for theoretical research such as TCM syndrome differentiation and treatment and prescription compatibility,and bring new opportunities for the modernization of TCM.
Essence of SyndromesMetagenomicsMicroorganismsModernization of TCM