Observation on the Clinical Efficacy of Targeted Intervention with Zhengqing Fengtongning Injection Combined with Hyperbaric Oxygen Therapy for Knee Osteoarthritis
Objective:To observe the clinical efficacy of Zhengqing Fengtongning Injection combined with hyperbaric oxygen therapy in the treatment of knee osteoarthritis(KOA).Methods:Ninety patients with knee osteoarthritis admitted to Nanchang 334 Hospital from January 2022 to January 2023 were randomly divided into Group A,Group B,and Group C,with 30 patients in each group.All three groups of patients received routine treatment,with group A receiving targeted intervention with Zhengqing Fengtongning Injection,group B receiving hyperbaric oxygen therapy,and group C receiving targeted intervention with Zhengqing Fengtongning Injection combined with hyperbaric oxygen therapy.The clinical efficacy,knee joint function[osteoarthritis index,visual analog scale(VAS)],and quality of life(arthritis impact assessment form)were compared among the three groups.Results:After two treatment courses,the total effective rate of the three groups was compared.Group C was 93.33%,while group A and group B were 76.67%and 66.67%,respectively.Group C was superior to group A and group B,and the difference was statistically significant(P<0.05);The osteoarthritis index and VAS of the three groups were lower than before treatment(P<0.05),and group C was lower than group A and group B,with statistically significant differences(P<0.05);The quality of life scores of all three groups were lower than before treatment(P<0.05),and group C was lower than group A and group B,with statistically significant differences(P<0.05).Conclusion:The targeted intervention of Zhengqing Fengtongning Injection combined with hyperbaric oxygen therapy has significant effects on the treatment of knee osteoarthritis,improving knee joint function and enhancing patients'quality of life.
Zhengqing Fengtongning InjectionHyperbaric Oxygen TherapyKnee OsteoarthritisQuality of Life