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复方柳菊胶囊中绿原酸和蒙花苷的含量分析

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目的:建立复方柳菊胶囊中绿原酸和蒙花苷的含量测定方法.方法:采用HPLC法测定复方柳菊胶囊中绿原酸和蒙花苷的含量,色谱柱为wondasic-C18 柱(250 mm×4.6 mm,5 µm);流动相为乙腈-0.1%磷酸水溶液,梯度洗脱;流速1 mL/min;检测波长 327 nm.结果:在考察的浓度范围内,绿原酸和蒙花苷呈现良好的线性关系;回收率和RSD值分别为98.66%、97.46%,0.86%、1.20%.结论:本方法准确度高、简便,可用于复方柳菊胶囊中绿原酸和蒙花苷的含量测定.
Content Analysis of Chlorogenic Acid and Buddleoside in Compound Liuju Capsule
Objective:To establish a method for the determination of chlorogenic acid and buddleoside in Compound Liuju Capsule.Methods:The chlorogenic acid and buddleoside in Compound Liuju Capsules were determined by HPLC.The separation was performed on a wondasic-C18 Column(250 mm×4.6 mm,5 μm)with a mobile phase of acetonitrile-0.1%phosphoric acid.The flow rate was 1 mL/min.The detection wavelength was 327 nm.Results:The chlorogenic acid and buddleoside showed a good linearity within the investigated concentration range.The recovery rate and RSD values were 98.66%,97.46%,0.86%,1.20%.Conclusion:The method is simple,accurate and can be used for the determination of chlorogenic acid and buddleoside in Compound Liuju Capsule.

Compound Liuju CapsuleChlorogenic AcidBuddleosideHPLC

李海兵、丘花花、杨金火

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鹰潭一八四医院 江西 鹰潭 335000

江西康恩贝天施康药业有限公司 江西 鹰潭 335000

复方柳菊胶囊 绿原酸 蒙花苷 HPLC

2024

10.20140/j.2095-7785.2024.06.20

江西中医药大学学报
江西中医学院

江西中医药大学学报

影响因子：0.575
ISSN：2095-7785
年,卷(期)：2024.36(6)