六神曲微生物菌群及功能性成分研究进展
Research Progress on Microbial Flora and Functional Components of Massa Medicata Fermentata
李雪艳 1罗钰颖 1杨华杰 1张雄 2金浩鑫 3杨双玲 1饶毅 1魏惠珍1
作者信息
- 1. 江西中医药大学 南昌 330004
- 2. 江西国都中药饮片有限公司 南昌 336000
- 3. 中药固体制剂制造技术国家工程研究中心 南昌 330006
- 折叠
摘要
发酵是借助微生物和酶的催化分解作用,改变原有药性、药效的一种炮制方法.六神曲作为中国传统发酵代表药之一,炮制过程中涉及多种微生物,且其中的微生物和六神曲药效成分的生物转化息息相关.现通过总结六神曲发酵过程中细菌与真菌多样性及其菌落动态变化,并对发酵前后其药效成分形成和药理作用研究进行综述,为进一步研究六神曲中功能微生物、优化炮制工艺和质量控制提供参考.
Abstract
Fermentation is a processing method to change the original medicinal properties and efficacy with the help of the catalytic decomposition of microorganisms and enzymes.Massa Medicata Fermentata,as one of the representative traditional medicines in China,involves a variety of microorganisms in the processing process,and the microorganisms are closely related to the biotransformation of medicinal components of Massa Medicata Fermentata.In this paper,the diversity of bacteria and fungi and the dynamic changes of their colonies during the fermentation of Massa Medicata Fermentata were reviewed,and the research on the formation of effective components and pharmacological effects before and after fermentation was also reviewed,which provided reference for further study of functional microorganisms in Massa Medicata Fermentata,optimization of processing technology and quality control.
关键词
六神曲/微生物/功能成分/药理作用/发酵Key words
Massa Medicata Fermentata/Microorganisms/Functional Components/Pharmacological Action/Fermentation引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据