In order to solve the problem of poor cooling effect of plate heat exchanger on oil-based drilling fluid,the influence of plate heat exchanger corrugated plate on the cooling performance of oil-based drilling fluid under different corrugation inclination,different corrugation pitch and different corrugation height was analyzed by numerical simulation method.The response surface experimental method was used,the response surface model was established with the cooling effect and treatment capacity as the comprehensive evaluation index,and the interaction between the parameters and the sensitivity of the three factors were analyzed.After the structural optimization,the temperature difference between the inlet and outlet of oil-based drilling fluid increased by 9.9 K compared with that before the structural optimization.The prediction and calculated values were verified,and the error of the comprehensive evaluation index is 4.95%.The research provides a reference for the field application of plate heat exchanger.