Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China

Key Laboratory of Otolaryngology Head and Neck Surgery(Ministry of Education of China),Beijing Institute of Otolaryngology,Beijing 100730,China

Department of Otorhinolaryngology,Head and Neck Surgery,The Chinese University of Hong Kong,Prince of Wales Hospital,Hong Kong SAR 999077,China

Department of Medical Genetics,Institute of Basic Medical Science,Chinese Academy of Medical Science &Peking Union Medical Collage,Beijing 100730,China