Application of Leiden Frost desorption assisted low-temperature plasma ionization mass spectrometry technology for detecting prohibited drugs in the environment
This study applied Leiden Frost desorption assisted low-temperature plasma ionization ion source and mass spectrometry to achieve rapid and highly sensitive detection of prohibited drugs in the environment.This tech-nology consists of two parts:a Leidenfrost thermal desorption device and a low-temperature plasma discharge ion source.The small droplets of the test sample are first thermally desorbed on the surface of the high-temperature heating rod,and then formed into[M+H]+by arc discharge,which is then detected by a mass spectrometer.By combining the high-voltage discharge power supply of the plasma generated by the arc with a quadrupole time-of-flight mass spectrometer,the device can be easily and quickly constructed,making experimental operations and sig-nal data detection more convenient and efficient.This method can quickly detect prohibited drugs in the environ-ment directly in the laboratory,with high sensitivity,strong practicality,low price,and does not require He,N2,and other auxiliary working gases.This device technology can not only detect drugs in the environment,but also be applied to food testing,military testing,biological analysis,environmental monitoring,and other fields.
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