The business office building is located in the high intensity area,and its structural system is reinforced concrete frame core tube.The south side frame columns of the bottom six floors all use folded columns.The third and sixth floors above ground are the floors where the turning points of the folded columns are located,and the core tube of the bottom two floors is offset.Therefore,the building belongs to a complex building structure.The overall analysis and time history analysis under frequent earthquake action,as well as the static elastoplastic deformation verification under rare earthquake action were carried out.The special analysis was carried out on the force transmission of the folded column,the stress of the floor at the folded point of the folded column and the design of the folded column joint.According to analysis results,strengthening measures were taken for the key components and parts from the aspects of calculation and construction,so that the seismic performance of the whole structure and each key component can reach the performance objectives of the design.In addition,the load is transmitted to the outer wall on the south side of the core tube by the inclined column at the top of the foundation,which has led to concentrated load on the south side of the core tube,causing uneven settlement of the foundation and tilting of the main structure.To address these issues,a series of measures were taken,such as stiffness variation leveling and cancellation of the post pouring strip,to control various indicators within the allowable range of the standards.