In view of the present teaching situation of organic chemistry course in pharmacy major of medical college,the author has explored and practiced the teaching idea,teaching content,teaching process and teaching evaluation,etc.It also puts forward a series of reform measures,such as improving the teaching level with double-subject teaching mode,improving the comprehensive quality with three-dimension training strategy,enriching the course content with four-fusion teaching method,etc.These measures not only overcome the drawbacks of the traditional teaching model,but also significantly improve the teaching level of teachers,and stimulate students'interest in learning,it provides useful experience and enlightenment for the reform of curriculum teaching in medical colleges and universities.