Clinical efficacy of domino liver transplantation:An analysis of two cases
Objective To investigate the clinical efficacy of domino liver transplantation(DLT)and to provide a refe-rence for expanding the sources of donor livers.Methods The clinical data of two cases who underwent DLT at our hospital in 2021 were collected,and a literature review was performed.Results Donor 1 was a healthy subject,recipient 1(DLT donor)was a patient with ornithine transcarbamylase deficiency,and recipient 2(DLT recipient)was a patient with Cirgler-Najiar syn-drome.Donor 2 was a brain-dead donor as per the internationally standardized definitions,recipient 3(DLT donor)was a patient with familial hypercholesterolemia,and recipient 4(DLT recipient)was a patient with malignant liver tumor.After transplanta-tion,all patients experienced recovery of their liver function in 1 week,and were discharged from the hospital after 2 to 4 weeks of hospitalization.Recipient 2 developed thrombosis in the left portal vein on day 4 after operation;after emergent thrombolysis and anticoagulant therapy,the blood flow of the portal vein was effectively improved,and no serious outcomes were identified;the bili-rubin level of the patient returned to normal at 1 week after operation.Recipient 4 developed hyperlipidemia after operation and was treated with atorvastatin and ezetimibe for lipid regulation;the patient was followed up till now with no additional complications found.Conclusion DLT can effectively expand the sources of donor livers.
国家科技期刊平台
NSTL
万方数据
维普
