Brain-gut axis is the two-way link between brain and gut nervous system.In recent years,research between gut symbiotic microorganisms and their animal hosts'neurophysiology and behaviors has grown exponentially and become one of the research hotspots and development directions in the related discipline.Researches showed that brain-gut axis plays an important role in regulating behaviors and physiological functions of insects.The effects of gut microbiota on insect foraging,movement,mating,aggression,learning and memory behavior,as well as social behavior are reviewed in this paper.The progress of research on the correlation between the brain-gut axis and human neurological diseases using insects as models is also summarized.