Efficacy of two drugs against apical periodontitis with sinus tract in flight personnel
Objective To investigate the efficacy of Vitapex paste and calcium hydroxide paste against apical periodontitis with sinus tract in flight personnel.Methods Sixty pilots with periapical periodontitis admitted to our hospital between 2019 and 2022 were selected as the subjects and randomly divided into two groups with 30 cases in each.The 30 patients treated with calcium hydroxide paste served as the control group while those treated with Vitapex paste combined with minocycline and ornidazole were assigned to the observation group.The therapeutic effect,levels of factors of inflammation and adverse reactions of the two groups were observed.Results The total effective rate was 100.00%in the observation group,compared with 76.67%in the control group,so the difference was statistically significant(χ2=5.822,P=0.016).There was no significant difference in VAS scores between the two groups before treatment(t=0.079,0.112,0.261,P=0.938,0.911,0.795),but the VAS score of the observation group was significantly lower than that of the control group 14 days after treatment(t=2.925,2.516,9.068,P=0.005,0.015,＜0.001).Adverse reactions included stomach discomfort,infections and headache.The incidence of adverse reactions was 10.00%in the observation group and 3.33%in the control group,so there was no significant difference between the two groups(χ2=0.268,P=0.605).Conclusion Vitapex paste combined with minocycline and ornidazole is effective in treating periapical periodontitis,which can help control bacterial infections of teeth of the flight personnel and quicken dental diagnosis and treatment during recuperation so that they can return to work sooner.
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